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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 1
1983 1
1987 1
1988 1
1989 1
1990 1
1991 2
1993 1
1995 1
1996 2
1997 2
1998 4
1999 5
2000 7
2001 5
2002 5
2003 4
2004 6
2005 7
2006 2
2007 8
2008 11
2009 7
2010 12
2011 6
2012 6
2013 12
2014 6
2015 2
2016 9
2017 10
2018 7
2019 12
2020 7
2021 14
2022 15
2023 20
2024 6

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216 results

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Page 1
Duplex-tetraplex equilibria in guanine- and cytosine-rich DNA.
Chalikian TV, Liu L, Macgregor RB Jr. Chalikian TV, et al. Biophys Chem. 2020 Dec;267:106473. doi: 10.1016/j.bpc.2020.106473. Epub 2020 Sep 7. Biophys Chem. 2020. PMID: 33031980 Review.
The tendency of a specific guanine- and cytosine-rich region of genomic DNA to adopt a four-stranded conformation depends on its ability to overcome the constraints of duplex base-pairing by undergoing consecutive duplex-to-coil and coil-to-tetraplex transitions. .. …
The tendency of a specific guanine- and cytosine-rich region of genomic DNA to adopt a four-stranded conformation depends on its ability to …
Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial.
Rovin BH, Barratt J, Heerspink HJL, Alpers CE, Bieler S, Chae DW, Diva UA, Floege J, Gesualdo L, Inrig JK, Kohan DE, Komers R, Kooienga LA, Lafayette R, Maes B, Małecki R, Mercer A, Noronha IL, Oh SW, Peh CA, Praga M, Preciado P, Radhakrishnan J, Rheault MN, Rote WE, Tang SCW, Tesar V, Trachtman H, Trimarchi H, Tumlin JA, Wong MG, Perkovic V; DUPRO steering committee and PROTECT Investigators. Rovin BH, et al. Lancet. 2023 Dec 2;402(10417):2077-2090. doi: 10.1016/S0140-6736(23)02302-4. Epub 2023 Nov 3. Lancet. 2023. PMID: 37931634 Clinical Trial.
The composite kidney failure endpoint was reached by 18 (9%) of 202 patients in the sparsentan group versus 26 (13%) of 202 patients in the irbesartan group (relative risk 0.7, 95% CI 0.4 to 1.2). Treatment-emergent adverse events were well balanced between sparsentan and …
The composite kidney failure endpoint was reached by 18 (9%) of 202 patients in the sparsentan group versus 26 (13%) of 202 patients in the …
Venous Ulcers.
Caprini JA, Partsch H, Simman R. Caprini JA, et al. J Am Coll Clin Wound Spec. 2013 Dec 4;4(3):54-60. doi: 10.1016/j.jccw.2013.11.001. eCollection 2012 Sep. J Am Coll Clin Wound Spec. 2013. PMID: 26236636 Free PMC article. Review.
This article presents an overview on some practical aspects concerning diagnosis, differential diagnosis and treatment. Duplex ultrasound investigations are essential to ascertain the diagnosis of the underlying venous pathology and to treat venous refluxes. ...Local treat …
This article presents an overview on some practical aspects concerning diagnosis, differential diagnosis and treatment. Duplex ultras …
The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum.
Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, Gloviczki ML, Lohr JM, McLafferty RB, Meissner MH, Murad MH, Padberg FT, Pappas PJ, Passman MA, Raffetto JD, Vasquez MA, Wakefield TW; Society for Vascular Surgery; American Venous Forum. Gloviczki P, et al. J Vasc Surg. 2011 May;53(5 Suppl):2S-48S. doi: 10.1016/j.jvs.2011.01.079. J Vasc Surg. 2011. PMID: 21536172 Free article.
The suggestions are weak (GRADE 2) if the benefits are closely balanced with risks and burden. The level of available evidence to support the evaluation or treatment can be of high (A), medium (B), or low or very low (C) quality. The key recommendations of these guidelines …
The suggestions are weak (GRADE 2) if the benefits are closely balanced with risks and burden. The level of available evidence to sup …
ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity.
Lamers MM, van den Hoogen BG, Haagmans BL. Lamers MM, et al. Front Immunol. 2019 Jul 25;10:1763. doi: 10.3389/fimmu.2019.01763. eCollection 2019. Front Immunol. 2019. PMID: 31404141 Free PMC article. Review.
Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are potent triggers of the innate immune system. ...However, this inhibitory effect must be overcome during viral infections. In this review we disc …
Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are pote …
Compression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis: the GAPS non-inferiority RCT.
Shalhoub J, Lawton R, Hudson J, Baker C, Bradbury A, Dhillon K, Everington T, Gohel MS, Hamady Z, Hunt BJ, Stansby G, Warwick D, Norrie J, Davies AH. Shalhoub J, et al. Health Technol Assess. 2020 Dec;24(69):1-80. doi: 10.3310/hta24690. Health Technol Assess. 2020. PMID: 33275096 Free PMC article. Clinical Trial.
MAIN OUTCOME MEASURES: The primary outcome measure was venous thromboembolism up to 90 days after surgery. A combined end point of duplex ultrasound-proven new lower-limb deep-vein thrombosis (symptomatic or asymptomatic) plus imaging-confirmed symptomatic pulmonary emboli …
MAIN OUTCOME MEASURES: The primary outcome measure was venous thromboembolism up to 90 days after surgery. A combined end point of duplex …
The Role of B7 Family Molecules in Maternal-Fetal Immunity.
Zhao Y, Zheng Q, Jin L. Zhao Y, et al. Front Immunol. 2020 Mar 24;11:458. doi: 10.3389/fimmu.2020.00458. eCollection 2020. Front Immunol. 2020. PMID: 32265918 Free PMC article. Review.
The upregulation and downregulation of maternal immunity executed by the leukocyte population predominantly depend on the activity of decidual natural killer cells and trophoblasts and are further modulated by a series of duplex signals. The B7 family, which consists of B7 …
The upregulation and downregulation of maternal immunity executed by the leukocyte population predominantly depend on the activity of decidu …
C-B-A Test of DNA Force Fields.
Strelnikov IA, Kovaleva NA, Klinov AP, Zubova EA. Strelnikov IA, et al. ACS Omega. 2023 Mar 6;8(11):10253-10265. doi: 10.1021/acsomega.2c07781. eCollection 2023 Mar 21. ACS Omega. 2023. PMID: 36969447 Free PMC article.
The DNA duplex may be locally strongly bent in complexes with proteins, for example, with polymerases or in a nucleosome. ...In the CHARMM force field, the B-form is a result of a fragile balance between the A-philic base stacking (especially for G:C pairs) and the …
The DNA duplex may be locally strongly bent in complexes with proteins, for example, with polymerases or in a nucleosome. ...In the C …
Regulation of DNA pairing in homologous recombination.
Daley JM, Gaines WA, Kwon Y, Sung P. Daley JM, et al. Cold Spring Harb Perspect Biol. 2014 Sep 4;6(11):a017954. doi: 10.1101/cshperspect.a017954. Cold Spring Harb Perspect Biol. 2014. PMID: 25190078 Free PMC article. Review.
., a protein that catalyzes homologous DNA pairing and strand exchange) assembles onto the ssDNA and promotes pairing with a homologous duplex. DNA synthesis then initiates from the 3' end of the invading strand, and the extended DNA joint is resolved via one of several pa …
., a protein that catalyzes homologous DNA pairing and strand exchange) assembles onto the ssDNA and promotes pairing with a homologous d …
Regulation of the Cerebral Circulation by Arterial Carbon Dioxide.
Hoiland RL, Fisher JA, Ainslie PN. Hoiland RL, et al. Compr Physiol. 2019 Jun 12;9(3):1101-1154. doi: 10.1002/cphy.c180021. Compr Physiol. 2019. PMID: 31187899 Review.
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and acid-base balance during deviations from homeostasis. Increases and decreases in the partial …
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the maintenance of cerebral metabolic homeostasis, a …
216 results